提醒在国内的亲友这些抗生素有副作用,不要乱吃(看来在澳洲求着医生开处方还真是事出有因)

加拿大卫生部近日对氟喹诺酮类（fluoroquinolones）抗生素的副作用表示担忧，称在极少数情况下该类药物不论口服还是注射都可能引发严重致残性副作用。

　　氟喹诺酮临床用于治疗尿路、肠道、呼吸道以及皮肤软组织、腹腔、骨关节等感染，常见药品包括：

　　环丙沙星Ciprofloxacin (Cipro)

　　莫西沙星Moxifloxacin (Avelox)

　　左氧氟沙星Levofloxacin

诺氟沙星Norfloxacin

　　氧氟沙星Ofloxacin

　　2008年起美国食品药品管理局FDA和加拿大卫生部就要求药商在氟喹诺酮类药品包装上明确标注药品可能引起跟腱断裂。

　　加拿大卫生部称新研究发现氟喹诺酮类药品副作用还包括周围神经病变以及中枢神经系统紊乱导致焦虑、眩晕。不良反应可能在服药几小时后或者几周后出现。

　　卫生部正与药商商讨将这些副作用标注在药品标签上。

　　卫生部还建议服药的病人如果出现不适症状要尽快咨询医生。

Health Canada expands warning for some antibiotics

A class of antibiotics called fluoroquinolones are associated with a range of persistent or disabling side-effects in rare cases, according to Health Canada.

Fluoroquinolones include oral and injectable antibiotics used to treat respiratory, urinary tract and other infections. The drugs are available as generic and brand name products including:

Ciprofloxacin (Cipro).

Moxifloxacin (Avelox).

Levofloxacin.

Norfloxacin.

Ofloxacin.

In 2008, the U.S. Food and Drug Administration and Health Canada asked makers of fluoroquinolone drugs to place a warning on the label that the drugs could lead to tendon ruptures.

Health Canada asks for tendon warning for some antibiotics

Now the Canadian regulator says a safety review suggests known side-effects include not only muscular issues such as tendonitis and Achilles tendon rupture, but also nerve damage such as peripheral neuropathy (damage to or a disorder affecting the nerves outside the spinal cord and brain), and central nervous system issues such as anxiety, dizziness and confusion.

Reactions can occur hours to weeks after taking a fluoroquinolone.

“As a result of its safety review, Health Canada is working with manufacturers to include information concerning this rare but serious risk in the product labelling of these drugs,” the regulator said Monday.

Health Canada said before taking a fluoroquinolone antibiotic, tell your health-care professional if you have previously experienced a side-effect related to its use.

If you experience side-effects such as joint and muscle pain, numbness, tingling or confusion while taking a fluoroquinolone, consult a health-care professional.

Researchers will also conduct more studies to better understand the use of fluoroquinolones in Canada, the regulator said.